There are millions of Americans who take vitamins or supplements every day, so you’re not alone. In addition to a healthy diet, there is evidence that some supplements can benefit your overall well-being with little to no risk.
Sadly, the supplement industry is also home to plenty of scammers who spread misinformation to hype questionable products and lure the unwary with deceptive marketing strategies.
It doesn’t matter whether you’ve been scammed yourself or if you would like to learn more, our reviews will give you the knowledge you need to spot and avoid scams with more confidence.
We have researched the brand Nature Made Vitamin B12 Supplement thoroughly in the past week to determine if it is a good supplement or just another waste of money.
In this Nature Made Vitamin B12 Supplement review, we’re going to cover the following to help you make an informed decision.
What is Nature Made Vitamin B12 Supplement?
Nature Made Vitamin B12 1000 mcg Softgels contains 150 softgels per bottle. USP has tested and verified the ingredients, potency and manufacturing process.
A deficiency or insufficiency can occur when levels of vitamin B12 become too low to meet the demands of the body. This can lead to a number of symptoms and can even progress to irreversible neurological issues if left untreated.
In the United States and United Kingdom, approximately 6% of adults aged 60 or younger have vitamin B12 deficiency. The rate jumps to 20% in people older than 60.
Vitamin B12 is a water-soluble vitamin, like all other B vitamins. This means it can dissolve in water and travel through the bloodstream. The body can store vitamin B12 for up to 4 years, and it can get rid of any excess or unwanted vitamin B12 in the urine.
Nature Made Vitamin B12 can promote metabolic health, help support nervous system function and convert food into cellular energy.
Along with other B vitamins, vitamin B12 is important for converting the food you eat into cellular energy. Vitamin B12 is also important for proper red blood cell formation and normal function of the nervous system.
Nature Made Vitamin B12 supplements may be important for vegetarians and vegans who avoid dietary sources rich in vitamin B12.
How Does Nature Made Vitamin B12 Supplement Work?
Vitamin B12 has many roles in your body. It supports the normal function of your nerve cells and is needed for red blood cell formation and DNA synthesis.
For most adults, the recommended daily intake (RDI) is 2.4 mcg, though it’s higher for women who are pregnant or breastfeeding.
Vitamin B12 may benefit your body in impressive ways, such as by boosting your energy, improving your memory and helping prevent heart disease.
Here are 9 health benefits of Nature Made vitamin B12 supplements, all based on science.
1. Nature Made Vitamin B12 Supplement Helps With Red Blood Cell Formation and Anemia Prevention
Vitamin B12 plays a vital role in helping your body produce red blood cells.
Low vitamin B12 levels cause a reduction in red blood cell formation and prevent them from developing properly.
Healthy red blood cells are small and round, whereas they become larger and typically oval in cases of vitamin B12 deficiency.
Due to this larger and irregular shape, the red blood cells are unable to move from the bone marrow into the bloodstream at an appropriate rate, causing megaloblastic anemia.
When you’re anemic, your body doesn’t have enough red blood cells to transport oxygen to your vital organs. This can cause symptoms like fatigue and weakness.
2. Nature Made Vitamin B12 Supplement May Prevent Major Birth Defects
Adequate vitamin B12 levels are crucial to a healthy pregnancy.
Studies show that a fetus’s brain and nervous system require sufficient B12 levels from the mother to develop properly.
Vitamin B12 deficiency in the beginning stages of pregnancy may increase the risk of birth defects, such as neural tube defects. Furthermore, maternal vitamin B12 deficiency may contribute to premature birth or miscarriage.
One study found that women with vitamin B12 levels lower than 250 mg/dL were three times more likely to give birth to a child with birth defects, compared to those with adequate levels.
For women with a vitamin B12 deficiency and levels below 150 mg/dL the risk was five times higher, compared to women with levels above 400 mg/dL.
3. Nature Made Vitamin B12 Supplement May Support Bone Health and Prevent Osteoporosis
Maintaining adequate vitamin B12 levels may support your bone health.
One study in more than 2,500 adults showed that people with a vitamin B12 deficiency also had lower than normal bone mineral density.
Bones with decreased mineral density can become delicate and fragile over time, leading to an increased risk of osteoporosis.
Other studies have also shown a link between low vitamin B12 levels and poor bone health and osteoporosis, especially in women.
4. Nature Made Vitamin B12 Supplement May Reduce Your Risk of Macular Degeneration
Macular degeneration is an eye disease that mainly affects your central vision.
Maintaining adequate levels of vitamin B12 may help prevent the risk of age-related macular degeneration.
Researchers believe that supplementing with vitamin B12 may lower homocysteine, a type of amino acid that is found in your bloodstream.
Elevated homocysteine levels have been associated with an increased risk of age-related macular degeneration.
The group receiving these supplements for seven years had fewer cases of macular degeneration, compared to the placebo group. The risk of developing any form of the condition was 34% lower, while it was 41% lower for more severe types.
Ultimately, further studies are needed to fully understand vitamin B12’s role in promoting vision health and preventing macular degeneration.
5. Nature Made Vitamin B12 Supplement May Improve Mood and Symptoms of Depression
Nature Made vitamin B12 supplement may improve your mood.
The effect of vitamin B12 on mood is not yet fully understood. However, this vitamin plays a vital role in synthesizing and metabolizing serotonin, a chemical responsible for regulating mood.
Therefore, vitamin B12 deficiency may lead to decreased serotonin production, which may cause a depressed mood.
Studies support the use of vitamin B12 supplements for improving symptoms of depression in people deficient in this vitamin.
One study in people with depression and low vitamin B12 levels found that those who received both antidepressants and vitamin B12 were more likely to show improved depressive symptoms, compared to those treated with antidepressants alone.
Another study discovered that vitamin B12 deficiency was associated with twice the risk of severe depression.
Additionally, high vitamin B12 levels have been linked to better treatment outcomes and an increased probability of recovery from major depressive disorder (MDD).
Though vitamin B12 supplements may help improve mood and depression in people with a deficiency, research does not currently suggest that they have the same effect in those with normal B12 levels.
6. Nature Made Vitamin B12 Supplement May Benefit Your Brain by Preventing the Loss of Neurons
Vitamin B12 deficiency has been associated with memory loss, especially in older adults.
The vitamin may play a role in preventing brain atrophy, which is the loss of neurons in the brain and often associated with memory loss or dementia.
One study in people with early-stage dementia showed that a combination of vitamin B12 and omega-3 fatty acid supplements slowed mental decline.
Another study found that even vitamin B12 levels on the low side of normal can contribute to poor memory performance. As a result, supplementing with this vitamin may improve memory, even in the absence of a clinically diagnosed deficiency.
More research is needed to make sound conclusions on the effect of vitamin B12 supplements on memory and cognitive function.
7. Nature Made Vitamin B12 Supplement May Give You an Energy Boost
Vitamin B12 supplements have long been touted as the go-to product for a surge of energy.
All B vitamins play an important role in your body’s energy production, though they don’t necessarily provide energy themselves.
Currently, there is no scientific evidence to suggest that vitamin B12 supplements can boost energy in those with sufficient levels of this vitamin.
On the other hand, if you’re significantly deficient in vitamin B12, taking a supplement or increasing your intake will likely improve your energy level.
In fact, one of the most common early signs of vitamin B12 deficiency is fatigue or lack of energy.
8. Nature Made Vitamin B12 Supplement May Improve Heart Health by Decreasing Homocysteine
High blood levels of the common amino acid homocysteine have been linked to an increased risk of heart disease.
If you’re significantly deficient in vitamin B12, your homocysteine levels become elevated.
Studies have shown that vitamin B12 helps decrease homocysteine levels, which may reduce your risk of heart disease.
However, there is currently no scientific evidence to confirm that vitamin B12 supplements are effective in this regard.
Therefore, further research is needed to understand the relationship between vitamin B12 and heart health.
9. Nature Made Vitamin B12 Supplement Supports Healthy Hair, Skin and Nails
Given vitamin B12’s role in cell production, adequate levels of this vitamin are needed to promote healthy hair, skin and nails.
In fact, low vitamin B12 levels can cause various dermatologic symptoms, including hyperpigmentation, nail discoloration, hair changes, vitiligo (the loss of skin color in patches) and angular stomatitis (inflamed and cracked mouth corners).
Supplementing with vitamin B12 has been shown to improve dermatologic symptoms in people with B12 deficiency.
However, if you’re well-nourished and not deficient in this vitamin, taking a supplement is unlikely to improve your skin, nail strength or hair health.
Can Nature Made Vitamin B12 Supplement Help You Lose Weight?
Although research in humans is still very limited, some studies suggest that vitamin B12 could affect body fat and metabolism.
One review concluded that vitamin B12 plays a key role in fat metabolism, noting that a deficiency could be linked to increased fat accumulation and obesity.
Another animal study found that severe vitamin B12 deficiency led to a significant increase in body fat percentage and cholesterol levels in pregnant mice.
What’s more, one animal study showed that administering B vitamins to rats fed a high fat diet reduced weight gain and increased levels of several enzymes that influence metabolism, compared with a control group.
However, current evidence is lacking, and additional high quality studies are needed to determine how Nature Made vitamin B12 supplement may affect metabolism and body fat in humans.
Having said that, several studies have found that having adequate vitamin B12 levels may be associated with a lower risk of weight gain and obesity.
According to one large study in 9,075 people, having higher blood levels of vitamin B12 was associated with a lower risk of obesity.
Similarly, another study in 976 people showed that having low levels of vitamin B12 was linked to a higher risk of being overweight or obesity.
What’s more, a study in 256 children showed that children with lower levels of vitamin B12 tended to have a higher body mass index (BMI), which is a measure of body size determined by height and weight.
However, keep in mind that while these studies show an association between vitamin B12 status and body weight, they don’t take other potentially contributing factors into account.
Therefore, it can’t be concluded that Nature Made vitamin B12 supplement causes weight loss.
More research is needed to determine whether vitamin B12 supplement directly affects body weight or BMI.
Who Is Nature Made Vitamin B12 Supplement For?
An estimated 6% of people in the US and UK aged 60 or older have vitamin B12 deficiency, while about 20% have low to normal or borderline deficient levels.
Vitamin B12 deficiency can occur in one of two ways. Either your diet lacks adequate amounts of it or your body is unable to fully absorb it from the food you eat.
Those at risk of vitamin B12 deficiency include:
- Older adults
- People with gastrointestinal disorders, such as Crohn’s disease or celiac disease
- Those who have had gastrointestinal surgeries, such as bariatric surgery or bowel resection surgery
- People on a strict vegan diet
- Those who take metformin for blood sugar control
- Those taking proton pump inhibitors for chronic heartburn
In many older adults, the secretion of hydrochloric acid in the stomach is reduced, causing a reduction in the absorption of vitamin B12.
If your body has difficulty absorbing vitamin B12, you might consider taking Nature Made vitamin B12 supplements to increase your levels.
Vitamin B12 is only found naturally in animal products.
Even though some plant-based milks or grains may have been fortified with vitamin B12, vegan diets are often limited in this vitamin, putting people at risk of deficiency.
If you eat a healthy, varied diet, preventing a vitamin B12 deficiency should be easy. However, if you think that you might be at risk, speak to your doctor.
Vitamin B12 deficiency can be prevented by taking Nature Made vitamin B12 supplements.
How To Use Nature Made Vitamin B12 Supplement?
Adults, take 1 softgel daily with water and a meal. Store tightly closed, in a cool, dry place, out of reach of children. Do not use it if the imprinted seal under the cap is broken or missing.
Nature Made Vitamin B12 Supplement Customer Reviews
As with any supplement, Nature Made Vitamin B12 Supplement has received both positive and negative feedback from customers. The effects can vary from person to person, after all.
Positive Nature Made Vitamin B12 Supplement Feedback
“Bought these for my little brother who was starting to lose his hair in small patches. (He’s 12) Our doctor reccommended taking b12 supplements. Tried these over 3 months and his hair has grown back. I now buy in bulk. Great product.” by Samantha Singh
“I never expected this to work. I just bought it because my doctor said I was deficient in Vit B and suggested a supplement. I am surprised. It improved my life and health in two different ways. It lifted my mood, it improved my energy levels and increased my metabolism. I am impressed, Highly so.” by exhiliration
Negative Nature Made Vitamin B12 Supplement Feedback
“Might be a good product but this B-12 arrived in a huge clump inside the bottle. Obviously shipped from a warm location as the pills were all stuck together. Sorry, it took me forever to tug them all apart. Wont be ordering this B-12 again.” by Jerrie
“Item contains soybean oil. Husband is allergic to soy. Cannot return. Please check info before purchasing this product.” by Francois
Nature Made Vitamin B12 Supplement Precautions and Side Effects
Doctors do not consider vitamin B12 as toxic in high quantities.
Hydroxocobalamin injections may cause side effects, including:
Serious side effects are rare. However, if people experience palpitations or signs of allergic shock after an injection, they should contact their doctor immediately.
Nature Made Vitamin B12 Supplement Ingredients
Nature Made Vitamin B12 Supplement has a unique formula. The product was created with natural ingredients and scientific backing. You can achieve the promised benefits by using the Nature Made Vitamin B12 Supplement on a regular basis.
Below is a list of the ingredients in Nature Made Vitamin B12 Supplement.
- Soybean Oil
- Yellow Beeswax
- Soy Lecithin
- Colors Added (Including Carmine)
- Vitamin B12
Final Verdict: Nature Made Vitamin B12 Supplement Reviews
Customers have given Nature Made Vitamin B12 Supplement positive reviews, but you should still speak with your healthcare provider before starting a new dietary regimen. Many supplements on the market have various ingredients and fillers. They can have side effects and may interact negatively with drugs. Therefore, you need proper guidance from your doctor to help you make the right decisions.
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