Alpha Brain Ingredients – Any Side Effects? Exposed!

Do you know the ingredients of Alpha Brain supplement? Are the ingredients in Alpha Brain safe for consumption?

Dietary supplements are products designed to augment your daily intake of nutrients, including vitamins and minerals. Normally, you should be able to get all the nutrients you need from a balanced diet. However, supplements can provide you with extra nutrients when your diet is lacking or certain health conditions trigger a deficiency.

While most dietary supplements are safe as long as you follow the product instructions, large doses of a certain ingredient can have adverse effects. Also, some may not contain the ingredients that they claim to have.

So understanding what ingredients Alpha Brain supplement contain is the most critical step before making a purchase.

Over the past few weeks, I have done thorough research about the ingredients of Alpha Brain supplement. So I can tell you whether it’s safe to consume Alpha Brain supplement.

I’m going to cover the benefits and potential side effects of the Alpha Brain ingredients in this article.

What are the Alpha Brain Ingredients?

Before we talk about the benefits and side effects of the Alpha Brain Ingredients, let me give you a brief overview of the ingredients used in Alpha Brain supplement.

Alpha Brain supplement contains the following ingredients:

  • Vitamin B6
  • L-Tyrosine
  • Oat straw Extract
  • Phosphatidylserine
  • Cat’s Claw Extract 
  • L-Alpha Glycerylphosphorylcholine (GPC)
  • Bacopa Extract
  • Huperzia serrata Extract
  • L-Leucine
  • Pterostilbene
  • Silica

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Vitamin B6

Vitamin B6, also known as pyridoxine, is a water-soluble vitamin that your body needs for several functions.

It’s significant to protein, fat and carbohydrate metabolism and the creation of red blood cells and neurotransmitters.

Your body cannot produce vitamin B6, so you must obtain it from foods or supplements.

Most people get enough vitamin B6 through their diet, but certain populations may be at risk for deficiency.

Consuming adequate amounts of vitamin B6 is important for optimal health and may even prevent and treat chronic diseases.

L-Tyrosine

​​Tyrosine is an amino acid that is naturally produced in the body from another amino acid called phenylalanine.

It’s found in many foods, especially in cheese, where it was first discovered. In fact, “tyros” means “cheese” in Greek.

It is also found in chicken, turkey, fish, dairy products and most other high-protein foods.

Tyrosine helps make several important substances, including:

  • Dopamine: Dopamine regulates your reward and pleasure centers. This important brain chemical is also important for memory and motor skills.
  • Adrenaline and noradrenaline: These hormones are responsible for the fight-or-flight response to stressful situations. They prepare the body to “fight” or “flee” from a perceived attack or harm.
  • Thyroid hormones: Thyroid hormones are produced by the thyroid gland and primarily responsible for regulating metabolism.
  • Melanin: This pigment gives your skin, hair and eyes their color. Dark-skinned people have more melanin in their skin than light-skinned people.

It’s also available as a dietary supplement. You can purchase it alone or blended with other ingredients, such as in a pre-workout supplement.

Supplementing with tyrosine is thought to increase levels of the neurotransmitters dopamine, adrenaline and norepinephrine.

By increasing these neurotransmitters, it may help improve memory and performance in stressful situations.

Oat straw Extract

Avena sativa, or common oat, is a species of cereal grass known for its highly nutritious seeds.

While its mature seeds are what become the oats you buy, oat straw extract comes from its stems and leaves, which are harvested earlier while the grass is still green.

Oat straw extract goes by many names, including green oat and wild oat extracts.

It’s high in iron, manganese, and zinc, though its nutrient composition can vary by brand.

The extract is claimed to offer many health benefits, including improvements in brain health, insomnia, stress, and physical and sexual performance.

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Phosphatidylserine

Phosphatidylserine is a fatty substance produced in the body that covers and protects cells and is involved in blood clotting. It’s particularly vital for the proper functioning of nerve cells within the brain, helping to transmit messages between them.

As an essential component of healthy nerve cell membranes, phosphatidylserine is thought to have a key role in keeping memory sharp. Studies in animals suggest that levels decline with age, and supplements may counteract this.

Phosphatidylserine is found naturally in certain foods and is also sold as a dietary supplement. Phosphatidylserine supplements are touted as a natural remedy for a variety of health conditions, including:

  • Attention deficit-hyperactivity disorder (ADHD)
  • Alzheimer’s disease
  • Anxiety
  • Depression
  • Multiple sclerosis
  • Stress

In addition, phosphatidylserine supplements are purported to preserve memory, promote healthy sleep, improve mood, and enhance exercise performance.

Cat’s Claw Extract 

Cat’s claw (Uncaria tomentosa) is a tropical vine which can grow up to 98 feet (30 meters) tall. Its name comes from its hooked thorns, which resemble the claws of a cat.

It is found mainly in the Amazon rainforest and in other tropical areas of South and Central America.

The two most common varieties are Uncaria tomentosa and Uncaria guianensis. The former is the type often used in supplements in the United States.

The bark and root have been used for centuries in South America as a traditional medicine for many conditions, such as inflammation, cancer, and infections.

Cat’s claw supplements can be taken as a liquid extract, capsule, powder, or tea.

L-Alpha Glycerylphosphorylcholine (GPC)

Alpha-GPC is a chemical released when a fatty acid found in soy and other plants breaks down. It is used as medicine.

In Europe alpha-GPC is a prescription medication for the treatment of Alzheimer’s disease. It is available in two forms; one is taken by mouth, and the other is given as a shot. In the United States alpha-GPC is only available as a dietary supplement, mostly in products promoted to improve memory.

Other uses for alpha-GPC include treatment of various kinds of dementia, stroke, and “mini-stroke” (transient ischemic attack, TIA). Alpha-GPC is also used for improving memory, thinking skills, and learning.

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Bacopa Extract

Bacopa monnieri, also called brahmi, water hyssop, thyme-leaved gratiola, and herb of grace, is a staple plant in traditional Ayurvedic medicine.

It grows in wet, tropical environments, and its ability to thrive underwater makes it popular for aquarium use.

Bacopa monnieri has been used by Ayurvedic medical practitioners for centuries for a variety of purposes, including improving memory, reducing anxiety, and treating epilepsy.

In fact, research shows that it may boost brain function and alleviate anxiety and stress, among other benefits.

A class of powerful compounds called bacosides in Bacopa monnieri is believed to be responsible for these benefits.

Huperzia serrata Extract

Huperzine A is a substance extracted from a plant called Chinese club moss (Huperzia serrata). Sold as a dietary supplement, huperzine A is typically touted as a treatment for Alzheimer’s disease.

Used in alternative medicine, huperzine A has been found to act as a cholinesterase inhibitor, a type of medicine used to prevent the breakdown of acetylcholine (a chemical essential to learning and memory).

Not only used as a treatment for Alzheimer’s disease, huperzine A is also said to enhance learning and memory and to protect against age-related cognitive decline.

In addition, huperzine A is sometimes used to boost energy, increase alertness, fight depression, and aid in the treatment of myasthenia gravis, an autoimmune disorder that affects the muscles.

L-Leucine

Protein is made up of amino acids and each source of protein has a unique amino acid profile.

Leucine, isoleucine and valine are known as branched-chain amino acids (BCAAs) and they provide energy during exercise, per the National Institutes of Health (NIH).

So what is leucine good for and what does is it do for your body? Amino acids play different roles in the body, primarily related to making proteins, per the U.S. National Library of Medicine.

As is the case with all essential amino acids, leucine cannot be produced by the body and must be obtained from food. While leucine is present in some plant-based foods (more on that below), it is generally higher in quantity and easier to find in food sourced from animals, per the NIH. That’s why plant-based diet followers should pay extra attention to their leucine intake.

Foods high in leucine include chicken, beef, pork, tuna, tofu, beans, milk, cheese, squash seeds and eggs, per the USDA.

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Pterostilbene

Pterostilbene is a dimethylated derivative of resveratrol that, for some mechanisms, is more potent. It is also much better absorbed, and is commonly referred to as a ‘better resveratrol’.

Silica

Silica is a natural compound, found all around us in nature. Silica makes up over a quarter of the planet’s crust and can be found in most rocks, clays and sands.

Its forms include emerald, quartz, clay and glass. Silica has multiple uses in industry – for example, in concrete – and in foods, including as an anti-caking agent.

Silica may help protect your heart health by reducing the risk of atherosclerosis, or hardening of the arteries, while lowering cholesterol, according to a 2018 report by the University of Memphis. The mineral can also support the immune response, and help to control inflammation in the body.

Benefits of Alpha Brain Ingredients

The ingredients in Alpha Brain supplement are carefully sourced and formulated. There are many benefits to your health.

1. May Prevent Clogged Arteries and Reduce Heart Disease Risk

Alpha Brain contains Pyridoxine HCI (B6). Vitamin B6 may prevent clogged arteries and minimize heart disease risk.

Research shows that people with low blood levels of vitamin B6 have almost double the risk of getting heart disease compared to those with higher B6 levels.

This is likely due to the role of B6 in decreasing elevated homocysteine levels associated with several disease processes, including heart disease.

One study found that rats deficient in vitamin B6 had higher blood levels of cholesterol and developed lesions that could cause artery blockages after being exposed to homocysteine, compared to rats with adequate B6 levels.

Human research also shows a beneficial effect of B6 in preventing heart disease.

A randomized controlled trial in 158 healthy adults who had siblings with heart disease divided participants into two groups, one that received 250 mg of vitamin B6 and 5 mg of folic acid every day for two years and another that received a placebo.

The group that took B6 and folic acid had lower homocysteine levels and less abnormal heart tests during exercise than the placebo group, putting them at an overall lower risk of heart disease.

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2. May Help Prevent Cancer

Alpha Brain contains Pyridoxine HCI (B6). Getting enough vitamin B6 may lower your risk of developing certain types of cancer.

The reason why B6 may help prevent cancer is unclear, but researchers suspect that it’s related to its ability to fight inflammation that may contribute to cancer and other chronic conditions.

A review of 12 studies found that both adequate dietary intake and blood levels of B6 were associated with lower risks of colorectal cancer. Individuals with the highest blood levels of B6 had an almost 50% lower risk of developing this type of cancer

Research on vitamin B6 and breast cancer also shows an association between adequate blood levels of B6 and a decreased risk of the disease, especially in postmenopausal women.

However, other studies on vitamin B6 levels and cancer risk have found no association.

3. May Improve Mood and Reduce Symptoms of Depression

Alpha Brain contain Vitamin B6. Vitamin B6 plays an important role in mood regulation.

This is partly because this vitamin is necessary for creating neurotransmitters that regulate emotions, including serotonin, dopamine and gamma-aminobutyric acid (GABA).

Vitamin B6 may also play a role in decreasing high blood levels of the amino acid homocysteine, which have been linked to depression and other psychiatric issues.

Several studies have shown that depressive symptoms are associated with low blood levels and intakes of vitamin B6, especially in older adults who are at high risk for B vitamin deficiency.

One study in 250 older adults found that deficient blood levels of vitamin B6 doubled the likelihood of depression.

However, using vitamin B6 to prevent or treat depression has not been shown to be effective.

A controlled two-year study in approximately 300 older men who did not have depression at the start found that those taking a supplement with B6, folate (B9) and B12 were not less likely to have depressive symptoms compared to the placebo group.

4. May Improve Mental Performance in Stressful Situations

Stress is something that everyone experiences.

This stress can negatively affect your reasoning, memory, attention and knowledge by decreasing neurotransmitters.

For example, rodents who were exposed to cold (an environmental stressor) had impaired memory due to a decline in neurotransmitters.

However, when these rodents were given a tyrosine supplement, the decline in neurotransmitters was reversed and their memory was restored. Alpha Brain contains tyrosine.

While rodent data does not necessarily translate to humans, human studies have found similar results.

In one study in 22 women, tyrosine significantly improved working memory during a mentally demanding task, compared to a placebo. Working memory plays an important role in concentration and following instructions.

In a similar study, 22 participants were given either a tyrosine supplement or placebo before completing a test used to measure cognitive flexibility. Compared to the placebo, tyrosine was found to improve cognitive flexibility.

Cognitive flexibility is the ability to switch between tasks or thoughts. The quicker a person can switch tasks, the greater their cognitive flexibility.

Additionally, supplementing with tyrosine has been shown to benefit those who are sleep deprived. A single dose of it helped people who lost a night’s sleep stay alert for three hours longer than they otherwise would.

What’s more, two reviews concluded that supplementing with tyrosine can reverse mental decline and improve cognition in short-term, stressful or mentally demanding situations.

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5. May improve blood flow

Research shows that impaired blood flow is a risk factor for heart disease and stroke.

Alpha Brain contains oat straw extract. Green oat extract contains a unique group of antioxidants called avenanthramides, which have been shown to improve heart health.

In particular, they may improve blood flow by increasing the production of nitric oxide, a molecule that helps dilate blood vessels.

One 24-week study in 37 older adults with excess weight found that supplementing with 1,500 mg of oat straw extract daily significantly improved measures of blood flow in the heart and brain, compared with a placebo.

6. May Improve Memory Loss

Alpha Brain contains Phosphatidylserine. Phosphatidylserine is often taken to try to slow age-related memory loss. In a study published in the Journal of Clinical Biochemistry and Nutrition, 78 older people with mild cognitive impairment were assigned to six months of treatment with phosphatidylserine supplements or a placebo.

In tests performed at the end of the six-month period, participants who took phosphatidylserine were found to have experienced a significant improvement in memory.

7. May Boost Your Immune System

Alpha Brain contains Cat’s claw. Cat’s claw may support your immune system, possibly helping fight infections more effectively.

A small study in 27 men found that consuming 700 mg of cat’s claw extract for 2 months increased their number of white blood cells, which are involved in combating infections.

Another small study in four men given cat’s claw extract for six weeks noted the same results.

Cat’s claw seems to work both by boosting your immune response and calming an overactive immune system.

Its anti-inflammatory properties could be responsible for its immune benefits.

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8. May help reduce ADHD symptoms

Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that is characterized by symptoms like hyperactivity, impulsivity, and inattentiveness.

Alpha Brain contains Bacopa monnieri. Interestingly, research has shown that Bacopa monnieri may help reduce ADHD symptoms.

One study in 31 children aged 6–12 years found that taking 225 mg of Bacopa monnieri extract daily for 6 months significantly reduced ADHD symptoms, such as restlessness, poor self-control, inattention, and impulsivity in 85% of the children.

Another study in 120 children with ADHD observed that taking an herbal blend that contained 125 mg of Bacopa monnieri improved attention, cognition, and impulse control, compared with the placebo group.

9. May boost brain function

Alpha Brain supplement contains Bacopa Monnieri. Research suggests that Bacopa monnieri may help enhance brain function.

For example, one study in mice showed that supplementing with Bacopa monnieri improved their spatial learning and ability to retain information.

The same study also found that it increased dendritic length and branching. Dendrites are parts of nerve cells in the brain that are closely linked to learning and memory.

Additionally, a 12-week study in 46 healthy adults observed that taking 300 mg of Bacopa monnieri daily significantly improved the speed of processing visual information, learning rate, and memory, compared with the placebo treatment.

Another 12-week study in 60 older adults found that taking either 300 mg or 600 mg of Bacopa monnieri extract daily improved memory, attention, and the ability to process information, compared with the placebo treatment.

10. May Help Treat Alzheimer’s Disease

Alpha Brain contains Huperzine A. Huperzine A appears to be of some benefit to people with Alzheimer’s disease, according to a 2013 research review published in PLoS One.

Researchers searched for all randomized controlled trials on the efficacy and safety of huperzine A for Alzheimer’s disease and concluded that huperzine A was more effective than a placebo in terms of its effects on cognitive function, behavioral disturbance, and functional performance. This was also found in a 2008 review published in Cochrane Database of Systematic Reviews.

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Side Effects of Alpha Brain Ingredients

When taken at the recommended doses, the ingredients in Alpha Brain supplement are generally safe to consume. However, you should bear in mind that some may cause side effects when used improperly.

For example, Alpha Brain contains cat’s claw. While side effects of cat’s claw are rarely reported, available information to determine its overall safety is currently insufficient.

The high levels of tannins in cat’s claw may cause some side effects — including nausea, stomach upset, and diarrhea — if consumed in large amounts.

Final Verdict: Are Alpha Brain Ingredients Safe or Harmful?

To conclude, the ingredients used in Alpha Brain supplement are generally safe for adults. They are natural ingredients that do not usually have any side effects, but it should not be used by kids or women who are pregnant or breastfeeding. All you need to do is follow the dosage instructions.

However, while there have been no reported side effects of Alpha Brain supplements in most healthy adults, you might still consult your doctor for double confirmation. 

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